Spironolactone to prevent edema while taking it

This has been a miracle drug for me. The quality of my life increased amazingly in the few months that I have been taking it. However, if you have any of the following symptoms you shouldn't be taking it and also there is a list of drugs it might interact with:

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spironolactone/hydrochlorothiazide:

Some medical conditions may interact with spironolactone/hydrochlorothiazide. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have cirrhosis or other liver problems, diabetes, gout, kidney problems (eg, kidney stones), asthma, heart problems (eg, heart failure), menstrual problems, or systemic lupus erythematosus (SLE or lupus)
• if you have high cholesterol or triglyceride levels, elevated blood acid, low folic acid levels, or electrolyte problems (eg, low blood sodium or magnesium levels), or are dehydrated
• if you have a history of high blood potassium levels or if your diet has a lot of potassium in it
• if you have recently had a certain type of nerve surgery (sympathectomy)
• if you have never taken medicines for high blood pressure or for swelling or fluid retention

Some MEDICINES MAY INTERACT with spironolactone/hydrochlorothiazide. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Cholestyramine because a severe side effect called metabolic acidosis may occur
• Aliskiren, angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), angiotensin II receptor antagonists (eg, valsartan), canagliflozin, cyclosporine, heparin or related products (eg, dalteparin, enoxaparin), macrolide immunosuppressives (eg, tacrolimus), other aldosterone-blockers (eg, eplerenone), other potassium-sparing diuretics (eg, amiloride, triamterene), potassium supplements, or salt substitutes containing potassium because the risk of high blood potassium levels may be increased
• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, indomethacin) because they may decrease spironolactone/hydrochlorothiazide's effectiveness, and the risk of high blood potassium or kidney problems may be increased
• Corticotrophin (ACTH), corticosteroids (eg, prednisone), or loop diuretics (eg, furosemide) because the risk of low blood potassium levels may be increased
• Barbiturates (eg, phenobarbital), diazoxide, digoxin, dofetilide, lithium, narcotic pain medicines (eg, codeine), or medicines for high blood pressure because the risk of their side effects may be increased by spironolactone/hydrochlorothiazide
• Insulin or other diabetes medicines (eg, glipizide) because their effectiveness may be decreased by spironolactone/hydrochlorothiazide

This may not be a complete list of all interactions that may occur. Ask your health care provider if spironolactone/hydrochlorothiazide may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

end quote from:http://www.drugs.com/cdi/spironolactone-hydrochlorothiazide.html

Spironolactone/hydrochlorothiazide: Indications, Side Effects ...

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Easy to read patient leaflet for spironolactone/hydrochlorothiazide. ... congestive heart failure, cirrhosis of the liver, or a certain kidney problem (nephrotic .... decreased urination or change in the amount of urine produced; dry mouth; excessive ...