Millions of GMO insects could be released in Florida Keys
KEY
WEST, Fla. (AP) — Millions of genetically modified mosquitoes could be
released in the Florida Keys if British researchers win approval to use
the bugs against two extremely painful viral diseases.
Associated Press
Millions of GMO insects could be released in Florida Keys
By JENNIFER KAY
5 hours ago
Never before have insects with modified DNA come so close to being set loose in a residential U.S. neighborhood.
"This
is essentially using a mosquito as a drug to cure disease," said
Michael Doyle, executive director of the Florida Keys Mosquito Control
District, which is waiting to hear if the Food and Drug Administration
will allow the experiment.Dengue and chikungunya are growing threats in the U.S., but some people are more frightened at the thought of being bitten by a genetically modified organism. More than 130,000 people signed a Change.org petition against the experiment.
Even
potential boosters say those responsible must do more to show that
benefits outweigh the risks of breeding modified insects that could bite
people.
"I think the science is fine, they definitely can kill
mosquitoes, but the GMO issue still sticks as something of a thorny
issue for the general public," said Phil Lounibos, who studies mosquito
control at the Florida Medical Entomology Laboratory.Mosquito controllers say they're running out of options. With climate change and globalization spreading tropical diseases farther from the equator, storm winds, cargo ships and humans carry these viruses to places like Key West, the southernmost U.S. city.
There are no vaccines or cures for dengue, known as "break-bone fever," or chikungunya, so painful it causes contortions. U.S. cases remain rare.
Insecticides
are sprayed year-round in the Keys' charming and crowded neighborhoods.
But Aedes aegypti, whose biting females spread these diseases, have
evolved to resist four of the six insecticides used to kill them.
Enter
Oxitec, a British biotech firm that patented a method of breeding Aedes
aegypti with fragments of genes from the herpes simplex virus and E.
coli bacteria as well as coral and cabbage. This synthetic DNA is
commonly used in laboratory science and is thought to pose no
significant risks to other animals, but it kills mosquito larvae.Oxitec's lab workers manually remove modified females, aiming to release only males, which don't bite for blood like females do. The modified males then mate with wild females whose offspring die, reducing the population.
Oxitec has built a breeding lab in Marathon and hopes to release its mosquitoes in a Key West neighborhood this spring.
FDA spokeswoman Theresa Eisenman said no field tests will be allowed until the agency has "thoroughly reviewed all the necessary information."
Company
spokeswoman Chris Creese said the test will be similar in size to
Oxitec's 2012 experiment in the Cayman Islands, where 3.3 million
modified mosquitoes were released over six months, suppressing 96
percent of the targeted bugs. Oxitec says a later test in Brazil also
was successful, and both countries now want larger-scale projects.
But
critics accused Oxitec of failing to obtain informed consent in the
Caymans, saying residents weren't told they could be bitten by a few
stray females overlooked in the lab.
Instead,
Oxitec said only non-biting males would be released, and that even if
humans were somehow bitten, no genetically modified DNA would enter
their bloodstream.
Neither claim is entirely true, outside observers say.
"I'm on their side, in that consequences are highly unlikely. But to say that there's no genetically modified DNA that might get into a human, that's kind of a gray matter," said Lounibos.
Creese says Oxitec has now released 70 million of its mosquitoes in several countries and received no reports of human impacts caused by bites or from the synthetic DNA, despite regulatory oversight that encourages people to report any problems. "We are confident of the safety of our mosquito, as there's no mechanism for any adverse effect on human health. The proteins are non-toxic and non-allergenic," she said.
Oxitec should still do more to show that the synthetic DNA causes no harm when transferred into humans by its mosquitoes, said Guy Reeves, a molecular geneticist at Germany's Max Planck Institute.
Key
West resident Marilyn Smith wasn't persuaded after Oxitec's
presentation at a public meeting. She says neither disease has had a
major outbreak yet in Florida, so "why are we being used as the
experiment, the guinea pigs, just to see what happens?"
___
Follow Jennifer Kay on Twitter at www.twitter.com/jnkay .
end quote from:
Millions of GMO insects could be released in Florida Keys
KEY
WEST, Fla. (AP) — Millions of genetically modified mosquitoes could be
released in the Florida Keys if British researchers win approval to use
the bugs against two extremely painful viral diseases.
Associated Press
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