Saturday, February 13, 2016

British DNA research on Human Embryos


  1. I've understood the Chinese have been doing this for some time. So, on one level it makes sense that someone in the western world would be doing it too, even if it horrific that human embryos are being researched upon. My wife said that it isn't live embryos they are researching. I'm not sure that's true but likely it is. However, this whole thing is a slippery slope for the western world at this point. 

    Whoops! I'm wrong this is research on Live Embryos. This is pretty disgusting! Because this is research on little live human beings.

  1.  BRITISH DEBATE EMBRYO RESEARCH - NYTimes.com

    www.nytimes.com/.../british-debate-embryo-research.html
    Oct 15, 1984 · DR. Robert Edwards, a British pioneer in the technique of in vitro fertilization that has produced almost 700 ''test tube'' babies around the world, has ...
  2. Jan 31, 2016 · British researchers get green light to genetically modify human ... The decision permits Niakan to study the embryos for 14 days for research purposes only.
  3. British Scientists Can Now Genetically "Edit"...

    mic.com/articles/134005/british-scientists-can-now...embryos
    A medical research institute was just given permission to edit human embryos. Last month, Dr. Kathy Niakan and her team at the Francis Crick Institute, a biomedical ... 

    British researchers get green light to genetically modify human embryos

    Scientists investigating miscarriage will not be able to implant embryos or study them for more than two weeks, says HFEA
    Kathy Niakan  next to a microscope
    Dr Kathy Niakan wants to look at the first few days of fertilisation. Photograph: Francis Crick Institute
    Britain’s first genetically modified human embryos could be created within months, after scientists were granted permission by the fertility regulator to carry out the procedure.
    The Human Fertilisation and Embryology Authority (HFEA) regulator approved a licence application by Kathy Niakan, a stem cell scientist at the Francis Crick Institute in London, to perform so-called genome editing – also called gene editing – on human embryos.
    The decision permits Niakan to study the embryos for 14 days for research purposes only. It does not permit them to be implanted into women. Niakan’s research is aimed at finding the genes at play in the early days of human fertilisation.
    The decision was greeted positively by the Francis Crick Institute and British scientists but was met with anger and disqmay by those concerned that rapid advances in the field of genome editing is precluding proper consideration of the ethical implications.
    Paul Nurse, director of the institute, said: “I am delighted that the HFEA has approved Dr Niakan’s application. Dr Niakan’s proposed research is important for understanding how a healthy human embryo develops and will enhance our understanding of IVF success rates, by looking at the very earliest stage of human development – one to seven days.”
    The work, using embryos donated by couples with a surplus after IVF treatment, will look at the fertilised egg’s development from a single cell to about 250 cells. The basic research could help scientists understand why some women lose their babies before term and provide better clinical treatments for infertility, using conventional medical methods.
    Niakan will use a powerful genome editing procedure called Crispr-Cas9 to switch genes on and off in early stage human embryos. She will then look for the effects the modifications have on the development of the cells that go on to form the placenta.
    Crispr-Cas9 has revolutionised biomedical research since its invention three years ago. It allows scientists to make precise changes to DNA, and has the potential to transform the treatment of genetic disorders by correcting faulty genes.
    Prof Robin Lovell-Badge, group leader at the Francis Crick Institute, said: “
    The approval of her [Niakan’s] licence gives the exciting prospect that we will at last begin to understand how the different cell types are specified at these pre-implantation stages in the human embryo.”
    Lovell-Badge said it would also provide invaluable information about the accuracy and efficiency of the technique, helping to inform the debate about whether genome editing could be used in future to correct faulty genes that cause devastating diseases.
    That prospect remains a long way off but is already a subject of concern.
    Dr David King, director of Human Genetics Alert, said: “This is the first step in a well mapped-out process leading to GM babies, and a future of consumer eugenics.” He claimed the government’s scientific advisers had already decided they were comfortable with the prospect of so-called “designer babies”.
    Anne Scanlan, from the anti-abortion organisation Life, said: “The HFEA now has the reputation of being the first regulator in the world to approve this uncertain and dangerous technology. It has ignored the warnings of over 100 scientists worldwide and given permission for a procedure that could have damaging far-reaching implications for human beings.”
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    There are fears that changes to an embryo’s DNA could have unknown harmful consequences throughout a person’s body and be passed on down the generations.
    Last year, leading UK funders called for a national debate on whether editing human embryos could ever be justified in the clinic. Some fear that a public backlash could derail less controversial uses of genome editing, which could lead to radical new treatments for conditions such as muscular dystrophy and sickle cell disease.
    The US National Institutes of Health will not fund any genome editing research on human embryos at present.
    But supporters of the HFEA’s decision said it had arrived at the right conclusion, balancing the benefits to research and ethical considerations.
    “The ruling by the HFEA is a triumph for common sense,” said Darren Griffin, a professor of genetics at the University of Kent.While it is certain that the prospect of gene editing in human embryos raised a series of ethical issues and challenges, the problem has been dealt with in a balanced manner. It is clear that the potential benefits of the work proposed far outweigh the foreseen risks.”
    Sarah Norcross, director of Progress Educational Trust, called it a victory for level-headed regulation over moral panic”.
    Dr Sarah Chan, chancellor’s fellow at Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, said: “We should feel confident that our regulatory system in this area is functioning well to keep science aligned with social interests.”
    end quote from:

    British researchers get green light to...

    How would you like to be one of the embryos they are doing research on?

    What is the morality here? Is it that an embryo not implanted in a womb doesn't have any rights at all and is treated a lot like a miscarriage or worse yet not even that status because it never started in a womb but was inseminated outside a womb through artificial insemination?

     



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