Thursday, December 4, 2014

International SOS for Ebola: December 4th 2014

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Last Updated: December 04, 2014 15:55 GMT  



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Suspected imported cases
4 December
Sierra Leone:
The Ministry of Health reports 26 deaths and 93 newly confirmed cases. Read more...
The latest World Health Organization Ebola response roadmap Situation Report states as at 30 November there have been a total of 17,145 cases and 6,070 deaths worldwide. The number of new cases is increasing in Sierra Leone, slightly increasing in Guinea and stable in Liberia. The case fatality rate in these three worst-affected countries is 72%, however it is lower (60%) amongst patients who are hospitalised. The United Nations Mission for Ebola Emergency Response (UNMEER) report that their targets of isolating and treating 70% of cases and burying 70% of people who die from Ebola by 1st December are likely to have been met. However there continue to be hard to reach hot-spot areas in remote locations which fall below these targets. Activities will need to be intensified in order to reach the targets of 100% by 1 January. See the individual country pages for further details.
Europe: Following the experience of health authorities in Spain, the European Centre for Disease Prevention and Control (ECDC) and the European Food Safety Authority (EFSA) have issued a joint statement on the risk of Ebola virus linked to household pets (pdf). Although much remains unknown, there is no current evidence that dogs or cats can develop the disease and transmit the virus. Risk assessments on pets in contact with human Ebola cases should be done jointly by veterinary and public health authorities on case-by-case basis. In animals, much of the natural history of the Ebola virus remains unknown and therefore, "the probability of a human becoming infected [after contact with an infected pet] could range from very low to high". Periods of isolation or home restriction may be considered for pets in contact with human cases.
United States: A US healthcare worker was medically evacuated to Atlanta on 4 December following possible exposure to Ebola in West Africa. Details are limited.
3 December
The latest World Health Organization situation summary reports a total of over 17,000 clinical cases and over 6,000 deaths in Guinea, Liberia and Sierra Leone as at 30 November. The total number of deaths has been revised down after more than 1,000 deaths in Liberia were removed from the count on 1 December, due to "ongoing reclassification, retrospective investigation and availability of laboratory results."
Sierra Leone: An additional 61 confirmed cases and 26 confirmed deaths were announced by the Ministry of Health. Read more...
2 December
Sierra Leone:
The Ministry of Health announced 27 confirmed deaths and 72 confirmed cases. The government also began preventing people from entering or leaving Tonkolili district (Northern province) in an effort to control the spread of Ebola. This measure will remain in place until 15 December. During this period, the borders of the district will be sealed and authorities will conduct a door-to-door awareness-raising campaign in the area. Visitors will not be allowed into the district, though vehicles passing through it will be allowed to enter, provided they do not stop.Read more...
Mali: One confirmed case remains hospitalised and no new cases have been identified as of 30 November. Read more...
Spain: The World Health Organization officially declared the Ebola outbreak in Spain over today. It has been 42 days (two Ebola incubation periods) since the country's single case recovered from infection.
1 December
Sierra Leone:
The Ministry of Health reports 75 newly-confirmed cases. Of the 138 health care workers who have been infected, 106 have died. Read more...
Italy: The doctor undergoing treatment in Rome is reported to be in a critical condition. He is receiving another dose of convalescent serum from a patient who recovered in Germany.
30 November
The latest World Health Organization situation summary for 28 November states there have been over 16,000 clinical cases reported in Guinea, Liberia and Sierra Leone. Nearly 7,000 Ebola-related deaths have been recorded in the three most affected countries in West Africa, however these numbers are likely to be underestimated.
Sierra Leone: There are an additional 64 confirmed cases reported by the Ministry of Health. Koinadugu district is under lockdown. Read more...
29 November
Mali:
The latest Ministry of Health (MoH) update advises that one Ebola patient has been discharged from the Bamako Ebola treatment unit after two tests were negative for the virus, while the other patient remains hospitalised at the treatment centre. News sources are reporting that all patients in Mali have recovered. An additional MoH announcement reports that over 280 contacts are still being monitored.
Italy: The doctor evacuated from Sierra Leone on 25 November and hospitalised in Rome is in declining health. He has developed nausea, vomiting, diarrhoea and rash. His high fever continues and he is profoundly weak. He is receiving three experimental antiviral medications, convalescent plasma and a medication that works within the immune system.
28 November
New rapid test for Ebola:
A rapid "point-of-care" Ebola test is being trialed in Conakry, Guinea. The trial is funded by the UK government and the Wellcome Trust, and overseen by researchers from the Pasteur Institute in Dakar, Senegal. The test can give results in 15 minutes, which could speed diagnosis dramatically if it proves reliable. Currently-available tests are slower and more difficult to use.
Summary of medical evacuations: The European Centre for Disease Prevention and Control reports there have been 22 international evacuations related to Ebola: seven into the USA, three each into Germany and Spain, two each into France and Switzerland, and one into the UK, Norway and Italy. Two healthcare workers repatriated to the Netherlands after exposure to Ebola did not have the disease.
Meanwhile the Lufthansa aircraft converted for medical transport of Ebola patients has been completed. The aircraft holds a negative pressure isolation unit capable of advanced intensive care treatment and has space for up to 19 seated passengers. Hundreds of crew members have volunteered to staff the plane if required.
Mali: No new cases have been confirmed. Two people are currently under treatment while over 280 contacts are being monitored. Read more...
Sierra Leone: The Ministry of Health reports 35 deaths and 88 newly-confirmed cases. The government announced a three-day shutdown of all businesses in the capital Freetown from 28 November. Read more...
Vaccines: Preliminary safety study results for the bivalent ChAd3-Ebola vaccine in Maryland, USA, look promising. Safety studies of the monovalent vaccine are ongoing in the USA, UK, Switzerland and Mali. Read more...
Liberia: Several new Ebola Treatment Units have opened up around the country, while the first two recovered health care workers have been discharged from the Monrovia Medical Unit. Media sources report that all beaches in the country will be closed on 29 November. Read more...
27 November
Italy:
Officials reported that the Italian doctor evacuated from Sierra Leone last week continues to have a fever. His condition is stable. He is being treated with an experimental drug, the details of which have not been disclosed.

Sierra Leone:
An additional 71 confirmed cases have been reported. Read more...
World Health Organization (WHO): The latest Ebola response roadmap situation report from states the total cases stands at nearly 16,000, including 5,689 deaths, as at 23 November. The case fatality rate is around 60% in the three intense-transmission countries. The increased rate of transmission in Sierra Leone continues to be a concern, while the overall situation is stabilising or declining in Liberia and Guinea. Cases connected to the Imam who died in Bamako have been identified in Mali. See the individual country pages for further information.
WHO and their partners continue to support 15 neighbouring countries in West Africa with technical assistance for their Ebola preparedness efforts.
26 November
Sierra Leone:
The Ministry of Health announced 81 new confirmed cases. A lack of safe burials is hampering disease control efforts in some areas. Another doctor has contracted Ebola. Read more...
25 November
Mali:
Another case has been reported by the Ministry of Health. Read more...

Sierra Leone: Additional new cases have been confirmed by the Ministry of Health. Read more...

24 November
Liberia:
The Ministry of Health states that Montserrado continues to report the most new cases and transmission continues in many counties. Read more...
Sierra Leone: There are 47 additional confirmed cases reported by the Ministry of Health. An Italian doctor who works for the non-governmental organisation "Emergency" has Ebola. He will be evacuated to Rome for further treatment. Read more...
23 November
France:
A United Nations healthcare worker has been discharged from a hospital in France after recovering from Ebola.
22 November
Sierra Leone:
Today's World Health Organization report states that a three-day lock-down is being proposed for Kumala, an area in Koinadugu that's currently a "hotspot" for new cases. Kumala is difficult to access and was the last area in the nation to be reached by the Ebola epidemic. Specimens and supplies are being transported by helicopter. Two of the three holding centres in Bombali are full. There have been 69 new cases, 51 of which are confirmed. Read more...
Mali: The Ministry of Health reports that another person tested positive for Ebola. The overall number of cases is seven with six deaths. Read more...
Research: Medecins Sans Frontieres will begin testing three experimental treatments for Ebola at their treatment centres next month. These are being fast tracked into human trials and are currently undergoing final regulatory and ethical approval.

  • Researchers from the University of Oxford, UK will test the antiviral brincidofovir. A treatment centre in Monrovia, Liberia is likely to be used in this trial.
  • A team from France's Institute of Health and Medical Research will test favipiravir, an antiviral developed for use against influenza. This trial will be carried out in Gueckedou, Guinea.
  • Researchers from Belgium's Antwerp Institute of Tropical Medicine will test convalescent whole blood and plasma treatment. The procedure involves taking antibody-containing blood or plasma from Ebola survivors and giving it to infected patients. This trial will take place in Conakry, Guinea.
Zmapp was not selected because of availability issues.
21 November
Mali:
A doctor has died from Ebola in Bamako. He was a contact of the Imam who died at the Pasteur Clinic.
Mali/Spain: A Spanish doctor working for Medecins Sans Frontieres in Mali will be repatriated to Madrid after a high-risk exposure incident (a needle stick). Read more...
Sierra Leone: The Ministry of Health announced 58 confirmed cases and 9 deaths for 20 November. Read more...
20 November:
Mali:
The cluster of cases linked to the sick Imam in Bamako now includes five people, four of whom died. Read more...
Sierra Leone: The Ministry of Health reported 43 newly-confirmed cases. Read more...
Sierra Leone/Cuba: The Cuban Ministry of Health confirmed that a doctor from Cuba has Ebola. He was part of a medical team that went to treat Ebola patients in Sierra Leone in early October. He is currently in the capital, Freetown, being cared for by doctors from the United Kingdom. He will be evacuated to the University Hospital of Geneva, Switzerland for further treatment.
WHO: The latest Situation Report by the World Health Organization states transmission is still increasing in Sierra Leone - particularly in the capital, Freetown, and the western and northern districts. The number of new cases reported in Guinea and Liberia is generally slowing except in hotspots such as Nzerekore in Guinea and the Liberian capital of Monrovia. See the individual country pages for further information.
The total number of clinical cases globally is now over 15,000 with more than 5,000 deaths. The report includes preliminary data about the progress of the 70-70-60 plan (70% of cases isolated, 70% of burials conducted in a safe manner, by the 60-day target of 1 December.) Eighteen of 56 planned Ebola Treatment Centres are now open. Encouragingly, 100% of the affected districts can now test samples within 24 hours of collection, and the number of new infections among health care workers has decreased.
CDC: The US Centers for Disease Control official stated today that it was "unlikely" that case numbers will reach 1.4 million by January, as previously predicted. He specifically said "We don't think the projections from over the summer will come to pass." He credits interventions and international support.
19 November
India:
An Indian man who was infected with Ebola while in Liberia - and recovered prior to travel - has been quarantined after returning to Delhi. He has no symptoms and no Ebola virus was detected in his blood, but it was present in his semen samples. Health authorities quarantined him to prevent transmission through sexual contact. He will be released when there is no longer any virus in his body fluids. It is normal for men to have Ebola in their semen after recovering from Ebola. The US CDC advises male Ebola survivors to abstain from sex (or to use condoms) for three months after they recover. See more on the FAQ of this website.
Sierra Leone: The Ministry of Health has reported 53 additional confirmed cases. A seventh Sierra Leonean doctor infected with Ebola has passed away. A Cuban doctor, part of the 165-member Cuban medical team sent to fight Ebola in Sierra Leone, has Ebola. He will be transported to Geneva for further treatment. Read more...
Liberia: The Ministry of Health reports that the number of new cases reported from Montserrado is increasing and transmission continues in several counties. Read more...
In other news, burial teams are being trained by the World Health Organization on safe sample collection from dead bodies. This will help diagnose the exact cause of death for patients and give more insight into the extent of the outbreak.
Mali: As contact tracing continues for the Bamako cluster, nearly 600 people are now under surveillance. An isolation centre will be set up in Kouremale.
Germany: Lufthansa airline, on behalf of the German Government, is transforming one of their A340 airplanes into an air ambulance. Three isolation units will be installed, allowing for evacuation of Ebola infected patients from West Africa. This air ambulance should be ready by the end of November. The German Government will make the air ambulance available to other nations for emergency evacuations.
18 November
Sierra Leone
: There are 89 newly-confirmed cases reported by the Ministry of Health. Read more...
Mali: The World Health Organization reports that there are now a total of 5 confirmed and 1 probable cases. All contacts of the 2-year-old index case in Kayes have completed the 21-day monitoring period. None of them had Ebola. Read more...
Liberia: The President has a set a goal of "zero new cases by Christmas."
17 November
Sierra Leone: An additional 54 confirmed cases have reported by the Ministry of Health. Read more...
United States: The infected doctor who was evacuated from Sierra Leone to Omaha, Nebraska, has died. Travellers from Mali will now be subjected to enhanced screening measures when they arrive in the U.S. Read more...
Mali: The Ministry of Health reports that the number of cases remains unchanged at 4 with 3 deaths. Over 442 contacts are under observation. Read more...
Aid: A Chinese medical team of 160 personnel have arrived in Liberia. It consists of medical experts, epidemiologists, doctors, nurses, engineers and technicians. They will manage the Ebola Treatment Unit at the Samuel Kanyan Doe Sports Stadium, which was built and funded by China.  end quote from:

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